ASEPTIC INFLAMMATION IN THE LUNGS IN ACUTE RADIATION SICKNESS
Inflammation in the lungs of irradiated rabbits at the site of turpentine injection has much in common with the inflammatory changes arising in other tissues and organs during local irradiation or acute radiation sickness. The fact that the inflammatory changes under different conditions of irradiation are similar in type regardless of the character of the inflammatory agent suggests that the phenomenon has a common mechanism. The absence of polymorphonuclear (eosinophtlic) leukocytes from inflammatory foci in irradiated rabbits is due not only to the developing leukopenia, but also to a disturbance of the leukocyte emigration process into the inflammatory focus. In irradiated rabbits in cortrast to the controls, the normal arrangement of the fibrous structures is preserved in the necrotic lung tissue at the site of turpentine injection. In animals with severe acute radiation sickness induced by external irradiation in sublethal doses, the ability of the organism to respond to introduction of an inflammatory agent by an increase in the number of leukocytes in the blood and by a rise of the body temperature is to some extent preserved. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-17-038890
- OSTI ID:
- 4645357
- Journal Information:
- Federation Proc., Transl. Suppl., Journal Name: Federation Proc., Transl. Suppl. Vol. Vol: 22
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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