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THE EFFECT OF ANTIBIOTICS ON THE INFLAMMATORY PROCESS IN IRRADIATED ANIMALS (in Russian)

Journal Article · · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR
OSTI ID:4264035

At the acute period of radiation sickness even a single massive dose of antibiotics may prevent the development of bacteremia and necrotic-hemorrhagic changes in places of microbe introduction, in case of an infection on the background of previously administered streptomycin or penicillin. However, in such inflammatory foci live microbes may be present for a long time. Numerous (for 5 days) intramuscular introduction of streptomycin almost completely destroys the microbes in inflammatory foci infected in 15 minutes following the first injection of the antibiotic. In intramuscular administration of streptomycin to irradiated and non-irradiated rabbits, the drop of the concentration of the antibiotic in the blood was in dependence to the dose introduced. (auth)

Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-13-009621
OSTI ID:
4264035
Journal Information:
Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 1; ISSN MERAA
Country of Publication:
Country unknown/Code not available
Language:
Russian

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