THE EFFECT OF STREPTOMYCIN AND PENICILLIN ON THE INFLAMMATORY PROCESS IN IRRADIATED ANIMALS

Journal Article · Wed Apr 01 04:00:00 EST 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4237278

Sosova, V F

The importance of the mode of intreduction, the number of administrations and the dose of the antibiotic (penicillin and streptomycin) in the treatment of infectious inflammation in irradiated rabbits (800 r) was studied. In the treatment of skin inflammatory foci, caused by the infection with B. coli, intramuscular administration of streptomycin was ineffective. The introduction of the antibiotic into the focus of inflammation reduced the number of microbes, the effect depending upon the quantity of bacteria in the tissus of the focus and on the dose of the antibiotic. In a number of instances upon introduction of streptomycin into the focus there developed very rapidly (in 24 hours) resistant forms of bacteria. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-015870
• OSTI ID: 4237278
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 4; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANTIBIOTICS
BACTERIA
BIOLOGY AND MEDICINE
DISTRIBUTION
EFFICIENCY
ESCHERICHIA COLI
INFECTIONS
MEDICINE
PENICILLIN
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
SENSITIVITY
SKIN
STREPTOMYCIN
THERAPY
TISSUES
VARIATIONS