THE INCORPORATION OF RADIOACTIVE PHOSPHORUS BY STRUCTURES OF THE HUMAN OVARY (in Italian)
Journal Article
·
· Rivista di Ostetricia e Ginecologia (Italy)
OSTI ID:4634763
The possibility that P/sup 32/ treatment of women of childbearing age may cause selective irradiation of follicular elements, and thus cause genetic damage, was investigated by radioautographic examination of the ovaries of women removed 48 hr after intravenous injection of 2 mu C P/sup 32/ per kg body wt. The relation of the amount of P/sup 32/ incorporated by various structures to the phases of the ovarian cycle was studied in particular. No uptake by the primordial follicles was noted. The granulosa cells of the maturing follicle showed a moderate uptake and those in the ripe follicle a marked uptake. Minor radioactivity was seen in the thecae interna and externa of ripe follicles, and little was present in atretic follicles. Uptake by corpora lutea and by the interstitial tissue was also low. However, on the basis of the appreciable incorporation of P/sup 32/, presumably in the nucleic acids of granulosa cells, in the proximity of the developing ovocyte, it was concluded that there is substantial risk of genetic injury to the ovum in women receiving this isotope. (BBB)
- Research Organization:
- Universita, Pisa, Italy
- NSA Number:
- NSA-17-038723
- OSTI ID:
- 4634763
- Journal Information:
- Rivista di Ostetricia e Ginecologia (Italy), Journal Name: Rivista di Ostetricia e Ginecologia (Italy) Vol. Vol: 16; ISSN ROGNA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Italian
Similar Records
Characterization of angiotensin I-converting enzyme (ACE)-containing follicles in the rat ovary during the estrous cycle and effects of ACE inhibitor on ovulation
Gonadotropin binding sites in human ovarian follicles and corpora lutea during the menstrual cycle
INFLUENCE OF THE ADMINISTRATION OF RADIOACTIVE PHOSPHORUS (P$sup 32$) ON THE GENITAL APPARATUS OF PUBERTAL AND PREPUBERTAL RATS
Journal Article
·
Fri Jun 01 00:00:00 EDT 1990
· Endocrinology; (USA)
·
OSTI ID:6699326
Gonadotropin binding sites in human ovarian follicles and corpora lutea during the menstrual cycle
Journal Article
·
Fri May 01 00:00:00 EDT 1987
· Obstet. Gynecol.; (United States)
·
OSTI ID:6501313
INFLUENCE OF THE ADMINISTRATION OF RADIOACTIVE PHOSPHORUS (P$sup 32$) ON THE GENITAL APPARATUS OF PUBERTAL AND PREPUBERTAL RATS
Journal Article
·
Sat Dec 31 23:00:00 EST 1960
· Arch. Ostet. Ginecol.
·
OSTI ID:4659005