Monte Carlo modeling of penetration effect for iodine-131 pinhole imaging

Journal Article · Sun Dec 01 04:00:00 EST 1996 · IEEE Transactions on Nuclear Science

DOI:https://doi.org/10.1109/23.552734· OSTI ID:458234

Wang, H; Jaszczak, R J; Coleman, R E ^[1]

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1. Duke Univ. Medical Center, Durham, NC (United States). Dept. of Radiology

Monte Carlo simulation was applied to model the penetration effect for iodine-131 pinhole imaging. In the authors` Monte Carlo simulation, the authors employed the variance reduction technique, forced detection, to improve simulation efficiency. For the forced detection, the minimal cone that covers the knife-edge region of a pinhole aperture was used to confine the direction of a photon emission with the vertex located at the emission point. A lead pinhole insert was used to validate the authors` Monte Carlo model. For the validation, the responses of a point source at six different locations along the central ray of the pinhole aperture were measured to compare with simulated responses. The range of distances for the source locations was 3--18 cm from the aperture with the inter-location distance equal to 3 cm. The comparison demonstrated the accuracy of the authors` Monte Carlo model. With the validated Monte Carlo program, the authors simulated point response functions for pinhole aperture with various aperture span angle, hole size, and materials. The point responses were parameterized using radially circularly symmetric two-dimensional exponential functions. The parameter describing the roll-off rate of an exponential function was expressed in terms of the span angle of the pinhole knife-edge opening and the material used to make the pinhole aperture. The parameterized penetration model can be incorporated into image reconstruction algorithms that compensate for the penetration effect.

• Sponsoring Organization: National Cancer Inst., Bethesda, MD (United States); USDOE, Washington, DC (United States)
• DOE Contract Number: FG02-96ER62150
• OSTI ID: 458234
• Report Number(s): CONF-951073--
• Journal Information: IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 6Pt2 Vol. 43; ISSN 0018-9499; ISSN IETNAE
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
ALGORITHMS
COLLIMATORS
COMPUTERIZED SIMULATION
DIAGNOSTIC TECHNIQUES
IMAGE PROCESSING
IODINE 131
MONTE CARLO METHOD
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY