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Increased nuclear diameter of gastric parental cells after x irradiation in the guinea pig

Journal Article · · Acta Pathol. Microbiol. Scand., Sect. A, Suppl., v. 81, pp. 591-592
OSTI ID:4413496
In the guinea pigs, diameters of parietal cell nuclei were measured at intervals of from 4 to 372 days after irradiation of the stomach. Five strips were cut from each stomach: one from the lesser curvature, two from the anterior and two from the posterior wall. Twelve parietal cell nuclei were measured in each section. The nuclei size increased significantly after irradiation, and the highest values were found after 4 days. Later on a gradual decrease seemed to take place. The marked increase of the parietal cell nuclear diameter might be an inherited sign of degeneration of the undifferentiated cells in the neck area of gastric glands, caused by x rays. The mechanism by which x rays increase nuclear diamieter is not clear. X irradiation might represent a useful technique for investigation of the various factors that influence the nuclear size. (DE)
Research Organization:
Originating Research Org. not identified
NSA Number:
NSA-29-008022
OSTI ID:
4413496
Journal Information:
Acta Pathol. Microbiol. Scand., Sect. A, Suppl., v. 81, pp. 591-592, Journal Name: Acta Pathol. Microbiol. Scand., Sect. A, Suppl., v. 81, pp. 591-592; ISSN APMSB
Country of Publication:
Denmark
Language:
English

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