Viruses in human tumors studied in fresh surgical material and in tissue culture
Technical Report
·
OSTI ID:4366000
BS>Radiological and Environmental Research Division annual report, July 1972-June 1973. Virus particles were isolated from a lung tumor from a patient who had a body burden of 1.6 mu Ci /sup 226/Ra grown in culture, as shown by their classical appearance in the electron microscope using negative staining techniques. No such particles were seen in normal lung tissue cultures. Virus- like particles were also seen with the electron microscope in thin sections prepared from surgically fresh material from the same tumor and in another adenocarcinoma, which exhibited similar foci-forming characteristics in culture. In a radium dial painter with a body burden of 1.6 mu Ci 30 years after ingestion similar virus-like particles were seen in fresh surgical material excised from a carcinoma of the mastoid. Speculation of the role of these viruses in the etiology of human cancer is premature before more carefully standardized work has been performed to study their identity and basic characteristics. (auth)
- Research Organization:
- Argonne National Lab., Ill. (USA)
- NSA Number:
- NSA-29-013034
- OSTI ID:
- 4366000
- Report Number(s):
- ANL--8060(Pt.2)
- Country of Publication:
- United States
- Language:
- English
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