Electron transfer in gamma-irradiated complexes between aromatic amino acids and DNA derivatives

Journal Article · Sat Dec 01 04:00:00 EST 1973 · Int. J. Radiat. Biol., v. 24, no. 6, pp. 589-594

DOI:https://doi.org/10.1080/09553007314551501· OSTI ID:4363664

Olast, M; Bertinchamps, A J

An ESR study of gamma -irradiated complexes between histamine and nucleotides, tryptamine and nucleosides, and between histamine and DNA showed that the spins were not distributed among the constituents following their radiosensitivity, but localized preferentially on the DNA derivatives. It is suggested that a transfer of electrons occurred, via the stacking of the molecules, during the anionic stage of their radiolysis, from the aromatic amino acids towards the DNA derivatives, i.e., towards the moiety presenting the highest electron affinity. It is suggested that these findings substantiate further the mechanism proposed previously in order to explain the spin transfers observed from purine towards pyrimidine nucleotides in complexes of these constituents. (auth)

• Research Organization: Univ., Brussels
• NSA Number: NSA-29-015395
• OSTI ID: 4363664
• Journal Information: Int. J. Radiat. Biol., v. 24, no. 6, pp. 589-594, Journal Name: Int. J. Radiat. Biol., v. 24, no. 6, pp. 589-594; ISSN IJRBA
• Country of Publication: United Kingdom
• Language: English

Related Subjects

AMINO ACIDS
CHEMICAL RADIATION EFFECTS
ELECTRON SPIN RESONANCE
ELECTRON TRANSFER
GAMMA RADIATION
HISTAMINE-- NUCLEOTIDES
N40300* --Chemistry--Radiation Chemistry
NUCLEOSIDES-- TRYPTAMINES
PURINES
PYRIMIDINES DNA-- HISTAMINE