Calculations related to the use of photons, neutrons, negatively charged pions, protons, and alpha particles in cancer radiotherapy

Technical Report · Tue Jan 01 04:00:00 EST 1974

DOI:https://doi.org/10.2172/4355851· OSTI ID:4355851

Alsmiller, Jr., R. G.; Santoro, R. T.; Armstrong, T. W.; Barish, J.; Chandler, K. C.; Chapman, G. R.

Calculated results are presented for absorbed dose, LET spectrum, and cell-survival probability as a function of position when photons, neutrons, negatively charged pions, protons, and alpha particles are incident on a tissue phantom. The beam parameters for each type of incident particle were chosen to be approximately those appropriate to the single-port irradiation of a small cylindrical volume (1 cm in radius and 2 cm in height) centered about a depth of 15 cm in the 30-cm-thick tissue slab. Both monoenergetic (15 MeV) neutrons and neutrons produced by 35-MeV /sup 2/H on Be are considered. The cell-survival- probability calculations are carried out using the model developed by R. Katz et al., and results are presented for both aerobic and anoxic T-l kidney ceils. Spatially dependent OER's and RBE's for each type of particle considered are also given. (auth)

• Research Organization: Oak Ridge National Lab., Tenn. (USA)
• DOE Contract Number: W-7405-ENG-26
• NSA Number: NSA-29-017455
• OSTI ID: 4355851
• Report Number(s): ORNL-TM--4369
• Country of Publication: United States
• Language: English

Related Subjects

*ALPHA PARTICLES-- RADIATION DOSES
*NEUTRONS-- RADIATION DOSES
*PHANTOMS-- RADIATION TRANSPORT
*PHOTONS-- RADIATION DOSES
*PIONS MINUS-- RADIATION DOSES
*PROTONS-- RADIATION DOSES
*RADIOTHERAPY-- RADIATION DOSES
KIDNEYS
LET
N72100* --Physics (Radiation & Shielding)--Radiation Physics
NEOPLASMS
TISSUES