Calculations pertaining to the use of fast (less than or equal to 50 MeV) neutrons in cancer radiotherapy
Calculated results are presented for a variety of neutron spectra incident on a tissue-equivale nt phantom. The neutron spectra considered are those produced by 35- and 50-MeV deuterons in a thick beryllium target and by 67- MeV protons in a thick lithium target. Results are presented for the absorbed doses, LET spectra, cell-survival probabilities, OERs, and RBEs as a function of position in the phantom. The cell-inactivation calculations were carried out using the model of Katz et al. and parameters for T-1 kidney cells. In the case of incident neutrons from 35-MeV /sup 2/H on Be, experimental and calculated absorbed-dose data are compared as a function of position in the phantom and are shown to be in good agreement. (auth)
- Research Organization:
- Oak Ridge National Lab., Tenn. (USA)
- DOE Contract Number:
- W-7405-ENG-26
- NSA Number:
- NSA-29-025859
- OSTI ID:
- 4333812
- Report Number(s):
- ORNL-TM--4442
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
*FAST NEUTRONS-- RBE
*RADIOTHERAPY-- NEUTRON SPECTRA
*TISSUE- EQUIVALENT MATERIALS-- NEUTRON SPECTRA
BERYLLIUM
DEUTERONS
KIDNEYS
LITHIUM
MEV RANGE 10-100
N68100 --Physics (Nuclear)--Neutron Interactions with Matter
N72100* --Physics (Radiation & Shielding)--Radiation Physics
OXYGEN ENHANCEMENT RATIO
PHANTOMS
PROTONS
TARGETS
*RADIOTHERAPY-- NEUTRON SPECTRA
*TISSUE- EQUIVALENT MATERIALS-- NEUTRON SPECTRA
BERYLLIUM
DEUTERONS
KIDNEYS
LITHIUM
MEV RANGE 10-100
N68100 --Physics (Nuclear)--Neutron Interactions with Matter
N72100* --Physics (Radiation & Shielding)--Radiation Physics
OXYGEN ENHANCEMENT RATIO
PHANTOMS
PROTONS
TARGETS