STEROL SYNTHESIS AFTER WHOLE BODY ROENTGEN IRRADIATION
Journal Article
·
· Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn.
Male rats were irradiated with 400 r whole body irradiation. The in vivo incorporation of 2-C/sup 14/-acetate in liver cholesterol decreases during the first day after irradiation and subsequently increases. The hepatic cholesterol concentration falls immediately, rises above normal and slowly falls again. Histology shows no change in cell population. Total radioactivity incorporated in liver tissue, as shown by autoradiographs reaches a maximum at l day after irradiation. Incubation of rat liver slices with 2-C/sup 14/acetate shows an increase in the metabolism of acetate to carbon dioxide, and an initial increase followed by a fall in the synthesis of digitonine-precipitable sterols from acetate. (auth)
- Research Organization:
- Radium Centre, Copenhagen, Denmark
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-12-002633
- OSTI ID:
- 4349293
- Journal Information:
- Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn., Journal Name: Acta Radiologica (Sweden) Divided into Acta Radiol.: Ther., Phys., Biol. and Acta Radiol., Diagn. Vol. Vol: 48; ISSN ACRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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