Morpho-functional changes in guinea pigs irradiated and protected with neurotropic drugs
Journal Article
·
· Radiobiol.-Radiother., v. 14, no. 5, pp. 613-618
OSTI ID:4346973
Luvatren (methylperiodol) and Surmontil (trimeprimin) in doses of 50 mgr/ kg and 120 mgr/kg respectively exhibited a radioprotective effect in guinea pigs irradiated with 800 R. An increased urinary elimination of 17- hydroxycorticosteroids and of 17-ketosteroids, more marked in protected guinea pigs, was observed in the first day after irradiation, tending to normalize in the following days. In contrast to the marked dystrophic-necrotic changes in the adrenals of irradiated and nonprotected guinea pigs, the dystrophic changes observed in the protected animal adrensis were more attenuated. (auth)
- Research Organization:
- Oncological Inst., Cluj
- NSA Number:
- NSA-29-021199
- OSTI ID:
- 4346973
- Journal Information:
- Radiobiol.-Radiother., v. 14, no. 5, pp. 613-618, Journal Name: Radiobiol.-Radiother., v. 14, no. 5, pp. 613-618; ISSN RDBGA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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