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Preparation and assessment of radioactive tracers

Journal Article · · Brit. Med. Bull., v. 30, no. 1, pp. 18-23
OSTI ID:4344685
An introduction to preparation of tracers for radioimmunoassay and saturation analysis is presented, and techniques are reviewed in outline under the following headings: properties required in the labeled antigen; preparation of labeled antigen; assessment of labeled antigen preparations; causes of iodination damage; alternative methods to the chloramine-T procedure i.e., enzymatic iodination of tyrosyl groups, gaseous diffusion of oxidant, conjugation labeling; limits of high specific activities, with particular reference to /sup 125/I and iodinated tracers for hapten-specific radioimmunoassay systems. (UK)
Research Organization:
Medical Research Council, Edinburgh
NSA Number:
NSA-29-027179
OSTI ID:
4344685
Journal Information:
Brit. Med. Bull., v. 30, no. 1, pp. 18-23, Journal Name: Brit. Med. Bull., v. 30, no. 1, pp. 18-23; ISSN BMBUA
Country of Publication:
United Kingdom
Language:
English

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