THE RELATIVE BIOLOGIC EFFECTIVENESS OF X-RAYS, GAMMA RAYS, AND FAST NEUTRONS IN THE PRODUCTION OF WEIGHT LOSS OF THE SMALL INTESTINE OF THE MOUSE

Technical Report · Fri Jan 17 04:00:00 EST 1958

OSTI ID:4338779

Patetta-Queirolo, M A; Randolph, M L; Sproul, Jr, J A

Groups of 10-week-old female RF mice were exposed to graded doses of CO/ sup 60/ gamma rays, 250-kvp x rays, or 14-Mev fast neutrons. The weight of the small intestine decreased during the first 48 hours after irradiation as a linear function of dose over the range 50 to 700 rads. No significant differences betw'een radiations in the production of this effect w'ere observed 1 day afier irradiation, but at 2 days the RBE was found to increase vaith LET, being 1.0, 1.5, and 2.0 for gamma rays, x rays, and neutrons, respectively. The RBE of neutrons for intestinal w-eight loss w-as appreciably higher than for 30-day lethality, in keeping with the hypothesis that the earlier mortality of mice exposed to neutrons, as opposed to x rays, results from relatively greater injury of the gastrointestinal tract by neutrons. (auth)

• Research Organization: Oak Ridge National Lab., Tenn.; School of Aviation Medicine, Randolph AFB, Tex.
• NSA Number: NSA-12-009571
• OSTI ID: 4338779
• Report Number(s): AF-SAM-58-72
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
COBALT 60
FAST NEUTRONS
GAMMA RADIATION
INTESTINE
LETHAL DOSE
MICE
RADIATION DOSES
RADIATION INJURIES
RBE
SEX
SURVIVAL TIME
VARIATIONS
WEIGHT
X RADIATION