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INCREASED PROTHROMBIN CONSUMPTION FOLLOWING TOTAL BODY X-IRRADIATION IN MAN

Journal Article · · Proc. Soc. Exptl. Biol. Med.
Hematological studies were carried out on 41 patients with disseminated neoplastic disease receiving therapeutic whole-body x irradiation. Increased prothromabin consumption, evidenced by an increase in the average serum prothrombin time, and in the incidence of prolonged serum prothrombin times, was found after irradiation. Greater sensitivity resulted when pure fibrinogen was used in place of prothrombin-free plasma in the one-stage serum prothrombin time test. Possible explanations for these findings were discussed. (auth)
Research Organization:
USAF School of Aviation Medicine, Randolph AFB, Texas
Sponsoring Organization:
USDOE
NSA Number:
NSA-12-003496
OSTI ID:
4318476
Journal Information:
Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 96
Country of Publication:
Country unknown/Code not available
Language:
English

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