THE EFFECT OF SUBLETHAL TOTAL BODY IRRADIATION ON THE BACTERICIDAL ACTIVITY OF RAT LEUCOCYTE MITOCHONDRIAL EXTRACTS
Technical Report
·
OSTI ID:4314094
S>Two different groups of rats were exposed to 300 and 500 r total-body x irradiation. Mitochondrial extracts were prepared from the leucocytes of these animals at various post-irradiation days. The bactericidal activity of these extracts was determined and compared to the activity obtained with extracts prepared from leucocytes from non-irradiated animals. The results showed that irradintion decreased the bactericidal activity per leucocyte, with the maximum depression occurring between the 3rd and 5th days after exposure. Recovery of the bactericidal activity was evident between the 8th and 12th post-irradiation day in the 300 r group but was not noted in the 500 r group even on the 30th day after irradiation. (auth)
- Research Organization:
- Naval Radiological Defense Lab., San Francisco
- NSA Number:
- NSA-12-004660
- OSTI ID:
- 4314094
- Report Number(s):
- USNRDL-TR-192
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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