CHANGES IN SOME ENZYMES IN EXPERIMENTAL RADIATION SICKNESS

Journal Article · Tue Jan 01 04:00:00 EST 1957 · Voprosy Rentgenol. i Onkol. (Erevan) Sbornik

OSTI ID:4153454

Shurkuryan, S G

Applicators with Co/sup 60/ were attached to the heads of rabbits, exposing them to a total dosage of 55,000 r. Blood was taken from the ear vein before irradiation and from the 4th to 30th day after irradiation. Catalase activity was determined by the Bach technique and carbonic anhydrase by the Brinkman method with the modification of Kreps. The carbonic anhydrase index was established by the erythrocyte count. Inactivation of catalase was observed after 3 to 4 days, was increased on the 8th to 16th day, and toward the 30th day its activity was gradualy restored. Activity of carbonic anhydrase fell as early as the 2nd day, was incompletely restored later on, and toward the 30th day was low. In younger rabbits, 2 to 3 months old, the activity of catalase and carbonic anhydrase persistently fell till the animals died. With a total dosage of 40,000 r the activity of catalase and carbonic anhydrase dropped until the 8th day and normalized later on. With total irradiation with Co/sup 60/ (total dose 900 r) the activities dropped sharply, and death occurred earlier.

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-14-023991
• OSTI ID: 4153454
• Journal Information: Voprosy Rentgenol. i Onkol. (Erevan) Sbornik, Journal Name: Voprosy Rentgenol. i Onkol. (Erevan) Sbornik Vol. Vol: 2
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOCHEMISTRY
BIOLOGY AND MEDICINE
BLOOD
CARBONIC ANHYDRASE
CATALASE
CHEMICAL REACTIONS
COBALT 60
ENZYMES
ERYTHROCYTES
IRRADIATION
LETHAL DOSE
METABOLISM
PERFORMANCE
QUALITATIVE ANALYSIS
QUANTITATIVE ANALYSIS
RABBITS
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
RADIATION SOURCES
REACTION KINETICS
SURVIVAL TIME
VARIATIONS
VEINS