INDUCED RECOVERY OF BLOOD-FORMING TISSUE IN IRRADIATED ANIMALS
Technical Report
·
OSTI ID:4310291
sters is enhanced by a single injectionof a bacterial endotoxin sure. This is invariably associated with an advance in hemopoietic recovery but is not necessarily associated with the increase in resistance to bacterial challenge or with the granulocytosis commonly seen within 24 hours after an endotoxin injection. Colchicine and several of its derivatives increase survival in mice when given a day or two prior to irradiation. The protective effect abruptly ceases at exposures which also is associated with an advance in the time of hemopoietic recovery. We have thus far seen no protection in animals given colchicine after irradiation. (auth)
- Research Organization:
- National Cancer Inst., Bethesda, Md.
- NSA Number:
- NSA-12-014528
- OSTI ID:
- 4310291
- Report Number(s):
- A/CONF.15/P/889
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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