ON THE NATURE OF THE DESTRUCTIVE PROCESSES TAKING PLACE IN THE SPLEEN OF MICE AS A RESULT OF EXPOSURE TO X-RAYS

Journal Article · Fri Aug 01 04:00:00 EDT 1958 · Doklady Akad. Nauk S.S.S.R.

OSTI ID:4301146

Barakina, N F

Effects of ionizing radiation on the cumulative changes in organisms were studied in order to determine the destructive changes in organs after direct and indirect exposures. Experiments were made with white mice weighing 18 to 20 g, one group of which was exposed to total-body irradiation. the second group exposed with a partial or complete screening of the spleen, and the third group with completely screened body with partial or complete exposure of the spleen Following the third day of exposure, the morphological changes in the spleen were similar in total-body or spleen-only exposure. A reverse picture was observed in total-body exposure with shielded spleen---no destruction of cells was observed in the spleen or in the shielded portion of it. The similarity of spleen changes in total and local irradiation and absence of any changes in the shielded portions indicate that mass cell destruction results from direct irradiation. However, the restorative processes are different in instances of local spleen exposure; the restoration takes place earlier than in the case of total body exposure. (R.V.J.)

• Research Organization: Severtsov Inst. of Animal Morphology, Academy of Sciences, USSR
• NSA Number: NSA-12-016105
• OSTI ID: 4301146
• Journal Information: Doklady Akad. Nauk S.S.S.R., Journal Name: Doklady Akad. Nauk S.S.S.R. Vol. Vol: 121
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

BIOLOGY AND MEDICINE
BODY
CONFIGURATION
CYTOLOGY
DISTRIBUTION
MICE
RADIATION DOSES
RADIATION INJURIES
REGENERATION
SHIELDING
SPLEEN
TISSUES
VARIATIONS
X RADIATION