VACCINE TULAREMIC INFECTION IN WHITE MICE IN CONDITION OF RADIATION SICKNESS (in Russian)
Preliminary irradiation of white mice by sublethal dose of x rays (370 r) causes acute decrease in natural immumity to vaccine tularemic infection. This is most pronounced if infection takes place within 2 to 24 hours after irradiation. It is clearly evident after 3 days, the infection decreases in 7 to 10 days, and disappears almost completely in introduction of vaccinal strain in 21 to 22 days following irradiation. There is a certain parallelism between the degree of depression of resistance of vaccine tularemic infection as a result of ionizing radiation and the decrease in the number of lymphocytes in the peripheral blood. Direct relationship is noted between the degree of depression of congenital immunity as a result of irradiation and the degree of multiplication of tularemic bacteria in the bone marrow and, partially, in the spleen. (tr-auth)
- Research Organization:
- Smolensk Med. Inst.
- NSA Number:
- NSA-13-000033
- OSTI ID:
- 4284746
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 3, No. 4; ISSN MERAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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