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CALCIUM-STRONTIUM DISCRIMINATION BY RAT SALIVARY GLANDS

Journal Article · · Proc. Soc. Exptl. Biol. Med.
Percent of administered dose in blood, kidney, and salivary gland was determined from 6 minutes to 16 hours after intravenous injection of a mixture of Ca/sup 45/ Sr/sup 85/. Salivary glands retained Ca/sup 45/ in preference to Sr/ sup 85/, reaching a ratio of 4.6: 1 at 16 hours. However, the glands showed a distinct retention of Sr/sup 85/ and contained 3.1 times the concentration in kidney 8 hours after injection. In secretion of saliva, the salivary glands showed less discrimination against Sr in favor of Ca than did uptake by the gland. After administration of tracer amount of Sr/sup 85/ or of 2.5 meq/kg of normal Sr, ratio of Ca/Sr was only slightly greater in saliva than that in serum. (auth)
Research Organization:
Stanford Univ., Calif.
Sponsoring Organization:
USDOE
NSA Number:
NSA-13-011584
OSTI ID:
4275319
Journal Information:
Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 100
Country of Publication:
Country unknown/Code not available
Language:
English

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