A STUDY OF CERTAIN INDICES OF NATURAL IMMUNITY IN DOGS AFFECTED BY POLONIUM, UNDER CONDITIONS OF COMBINED THERAPY. I. A STUDY OF THE INTESTINAL MICROFLORA

Journal Article · Tue Dec 31 23:00:00 EST 1957 · J. Microbiol., Epidemiol. Immunobiol. (USSR) (English Translation)

OSTI ID:4264163

Nemirovich-Danchenko, O R

S>The subcutaneous injection of polonium in a dose of 0.05 mc/kg body weight caused severe radiation sickness in dogs. Changes were observed in the intestinal microflora. These included a fall in the number of typical E. coli and an increase in the proportion of hemolytic strains among the intestinal flora, a rise in the number of atypical strains of E. coli, and a rise in the numbers of Cl. perfringens during the first few days of radiation sickness. The institution of combined therapy led to some improvemeut in the general condition of the animals, increased their survival time, suppressed the development of local inflammatory changes at the site of injection of the polonium and led to the relative normal zation of the microflora of the large intestine. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-017704
• OSTI ID: 4264163
• Journal Information: J. Microbiol., Epidemiol. Immunobiol. (USSR) (English Translation), Journal Name: J. Microbiol., Epidemiol. Immunobiol. (USSR) (English Translation) Vol. Vol: 29
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BACTERIA
BIOLOGY AND MEDICINE
BODY
CLOSTRIDIUM PERFRINGENS
DOGS
EFFICIENCY
ESCHERICHIA COLI
IMMUNITY
INTESTINE
MEDICINE
POLONIUM
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
SKIN
SURVIVAL TIME
THERAPY
VARIATIONS
WEIGHT