CHANGES IN INTESTINAL MICROFLORA IN X-IRRADIATED RATS (in Polish)
Transistory bacteremia and intestinal microflora in x-irradiated rats were studied. Rats were subjected to total-body doses of 900 r and killed at different times after irradiation. Liver, spleen, and kidney were examined for presence of bacteria, and fecal material from jejunum, colon, and cecum was also used for bacteriological examination. From the internal organs of the irradiated rats, Escherichia coli and Proteus bacteria were isolated 4, 6, and 7 days after irradiation. The same bacterial strains were found in the intestines. This suggests that the presence of bacteria in internal organs was caused by the autoinfection from the intestine. The qualitative changes of intestinal microflora are described. The most distinctive changes were observed in the jejunum of irradiated animals. The ascendence of E. coli and Clostridium species into jejunum was noted; at the same time Streptococcus faecalis became rare. Sensitivity to antibiotics of the isolated strains was determined. (H.H.D.)
- Research Organization:
- Wojskowy Inst. of Hygiene and Epidemiology, Warsaw
- NSA Number:
- NSA-17-027074
- OSTI ID:
- 4698588
- Journal Information:
- Acta Microbiol. Polon., Journal Name: Acta Microbiol. Polon. Vol. Vol: 11
- Country of Publication:
- Country unknown/Code not available
- Language:
- Polish
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