THE PROPHYLAXIS OF RADIATION SICKNESS

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4264004

Antipov, V V; Krasnykh, I G

Experiments were performed on 392 mice to assess the protective effects of para-aminopropiophenone and its formaldehydebisulfate derivative and para- aminobuterophenone against x irradiation. The preparations were introduced into the esophagus one to three hours prior to irradiation. The first two agents were administered in a 20% ethyl alcohol solution, the third tn 0.5% aqueous solution. The doses were 50 to 100 mp/kg body weight. The animals were irradiated wtth the dose of 900 r. The investigations revealed that the largest protective effect is possessed by paraaminopropiophenone and its formaldehydebisulfate derivative in the dose of 50 mg/kg body weight, introduced one hour before irradiation. 20 to 25% of mtce survived in this method of administration. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-009625
• OSTI ID: 4264004
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 1; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ALCOHOLS
ALDEHYDES
BIOLOGY AND MEDICINE
EFFICIENCY
FORMIC ACID
INTESTINE
KETONES
MICE
PAPP
RADIATION DOSES
RADIATION PROTECTION
RADIATION SICKNESS
SOLUTIONS
SULFATES
SURVIVAL TIME
TESTING
WATER
X RADIATION