THE INFLUENCE OF INTRODUCTION OF BONE MARROW SUSPENSION OF THE IMMINITY OF IRRADIATED ANIMALS

Journal Article · Wed Jul 01 04:00:00 EDT 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4263979

Tumanyan, M A; Izvekova, A V

Experimental investigations show that daily protracted (20 to 25 days) treatment with bone marrow following the action of ionizing radiation stimulates hematopoiesis. Prolonged daily administration of bone marrow of nonirradiated rats (80 to 100 million cells) into the irradiated rats increases the number of leukocytes, erythroeytes, thrombocytes, and reticulocytes in comparison with the control. The introduction of bone marrow raises the sharply lowered natural resistance of rats to typhoid bacteria due to the influence of ionizing radiation. Bone marrow administration to rats irradiated with LD100 of gamma-rays increases their survival rate up to 30%. Although the treatment of irradiated rats with antibioties and bone marrow does not increase their survival rate as compared with the irradiated rats treated only with antibiotics, however, the above treatment produces the most favorable effeet of protection of the irradiated organism from infectious complications of radiation sickness. (auth)

• Research Organization: Gamalei Inst. of Epidemiology and Microbiology
• NSA Number: NSA-13-017719
• OSTI ID: 4263979
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 7; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANTIBIOTICS
BIOLOGY AND MEDICINE
BLOOD CELLS
BLOOD FORMATION
BONE MARROW
CYTOLOGY
ERYTHROCYTES
GAMMA RADIATION
IMMUNITY
LETHAL DOSE
LEUCOCYTES
PLATELETS
QUANTITY RATIO
RADIATION PROTECTION
RADIATION SICKNESS
RATS
RETICULOCYTES
SURVIVAL TIME
SUSPENSIONS
TRANSPLANTS
VARIATIONS