CERTAIN DATA CONCERNING THE EFFECT OF IRRADIATION ON HAEMOPOIESIS OF SPLENECTOMIZED RATS (in Russian)
An attempt was made to find out the influence of the spleen on bone marrow after general irradiation of animals by x ray. One group of white rats was splenectomized 1 1/2 months before irradiation, which was performed with the aid of RUM-3 apparatus. The dose of irradiation was 400 r which is the lethal dose for rats in 50 to 30 days. The animals were subjected to haemotological examination before splenectomy, before irradiation and on the 4th, 11th and 2Oth day after irradiation. The number of leukocytes, erythrocytes, thrombocytes and reticulocytes was determined and differential count of leukocytes made. It was revealed by this experiment that lymphocytosis and eosinophilia (in majority of cases) is developed in rats in remote time-limits after splenectomy. In all other respects their blood remained normal. Examinations of peripheral blood and bone marrow show the influence of the spleen on the bone marrow of irradiated rats. These experiments reveal thnt spleen has a retarding effect on all forms of haemopoieses in the bone marrow. The mechanism of this action is not specific for radiation sickness. (tr-auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-13-002675
- OSTI ID:
- 4313374
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: No. 5; ISSN MERAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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