THE USE OF TRITIATED THYMIDINE IN THE STUDY OF DNA SYNTHESIS AND CELL TURNOVER IN HEMOPOIETIC TISSUES
Journal Article
·
· Laboratory Investigation (U.S.)
OSTI ID:4254310
Thymidine labeled with tritium was used in a series of in vivo and in vitro studies of desoxyribonucleic acid synthesis and turnover in hematopoietic tissues. Problems associated with tritium autoradiography are reviewed, and the effects of radiation from injected tritium are discussed. Results indicate a rapid incorporation of thymidine into the hematopoietic tissues throughout the body. Evidence is presented for the existence of cells circulating in the peripheral blood of normal human beings capable of synthesizing desoxyribonucleic acid and thus able to divide at least once again. Characteristics of this group of cells are described. (C. H.)
- Research Organization:
- Brookhaven National Lab., Upton, N.Y.
- NSA Number:
- NSA-13-007412
- OSTI ID:
- 4254310
- Journal Information:
- Laboratory Investigation (U.S.), Journal Name: Laboratory Investigation (U.S.) Vol. Vol: 8; ISSN LAINA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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