ATTEMPTS TO REPRODUCE CIRRHOSIS OF THE LIVER IN RATS FOLLOWING TOTAL-BODY X- IRRADIATIONS
Technical Report
·
OSTI ID:4247472
A histopathological study of the liver following whole body x irradiation was made using a low protein diet as a tool for amplifying latent injury. Experiments were designed so that rats were placed on the experimental diet before exposure, during exposure, at the end of the exposure period or after an extended period of recovery from the acute radiation illness. Whole-body x irradiation, either 475 r in a single exposure of 200 r/week for 5 consecutive weeks, had no demonstrable effect upon onset or severity of cirrhotic lesions when compared to nonirradiated rats on the same diet for the same period of time. Fibrous lesions of the liver in these experiments appear to be dietary in origin and were all but eliminated by cholorine supplementation. (auth)
- Research Organization:
- Naval Radiological Defense Lab., San Francisco
- NSA Number:
- NSA-13-011540
- OSTI ID:
- 4247472
- Report Number(s):
- USNRDL-TR-304
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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