A STUDY OF THE EFFECTS OF TOTAL AND PARTIAL BODY RADIATION ON IRON METABOLISM AND HEMATOPOIESIS. Progress Report for Period September 1, 1958-November 30, 1958
Results are reported from a study of the response of red blood cell count and hemoglobin levels to three types of interference that may be looked upon as traumatic stimuli. These include plasma transfusions extracorporeal circulation of bloods and irradiation of blood in extracorporeal circulation. These represent different magnitudes of trauma. Transfusion is minimal, extracorporeal circulation somewhat greater, and irradiation of blood in extracorporeal circulation seems distinctly to add an additional factor to injury. Injury is followed by recovery. For a more severe injury, recovery tends to achieve levels above initial values for hemoglobin and red blood cell counts. Whether the addition of irradiation in these experiments represents merely quantitatively greater trauma, or whether it is qualititiveiy different trauma, is not established. The observation of similar prolongation of depression and recovery in dogs transrused with irradiated plasma does permit the possibility that blood irradiated in extracorporeal circulation does sustain injury beyond that due to the mechanical procedure alone. (auth)
- Research Organization:
- Baylor Univ., Houston, Tex. Coll. of Medicine; Jefferson Davis Hospital, Houston, Tex.
- NSA Number:
- NSA-13-014969
- OSTI ID:
- 4243232
- Report Number(s):
- AD-208454
- Country of Publication:
- United States
- Language:
- English
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