THE EFFECTS OF WHOLE-BODY RADIATION ON HEMORRHAGIC SHOCK
Technical Report
·
OSTI ID:4243152
ABS>Male albino rats of an inbred strain were subjected to sublethal doses of whole-body radiation. They were then subjected to hemorrhagic shock which, in itself, was nonlethal on either the first, fifth, tenths or twentieth day postirradiation. The response to hemorrhage, as well as the ultimate survival of the animals, was studied. It was found that there was a mutual enhancement of the radiation effect and the sensitivity to hemorrhagic shock. This enhancement was most noted in animals subjected to hemorrhagic shock during the second and third week. postirradiation. There was no alteration in the response to shock or radiation in the group of animals subjected to shock on the first day postirradiation. This potentiation occurs during the recovery phase from irradiation and does not seem to be related to endogenous bacteremia or the suppression of the white blood count or red cell mass resulting from whole-body irradiation. (auth)
- Research Organization:
- Walter Reed Army Medical Center. Inst. of Research, Washington, D.C.
- NSA Number:
- NSA-13-014988
- OSTI ID:
- 4243152
- Report Number(s):
- WRAIR-76-57; AD-151794
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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