SPECIFIC FEATURES OF POSTOPERATIVE COURSE AND RADIATION SICKNESS IN DOGS SUBJECTED TO X-RAY IRRADIATION

Journal Article · Wed Apr 01 04:00:00 EST 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4242244

Gamaleya, A N; Gyurdzhian, A A; Koshkin, A F; Nekrasov, F P; Simonov, P V

The experiments were staged on 34 large dogs. Eleven of them were subjected to x irradiation in doses (600-650 r) provoking a severe course of acute radiation sickness, and subsequent operation-resection of 20 cm of the small intestine. Eleven dogs were subjected only to irradiation and 12 only operated upon. The operation was performed under ether narcosis 4-5 hours following irradiation. Comparison of the clinical picture of these three groups of animals enabled to draw the following conclusions. The results of the operation and the postoperative course in the irradiated dogs did not divulge any noticeable deviation and unfavorable course of the disease as compared to the group, of andmals, which were not irradiated. The above concerns only those instances, when the onset of radiation sickness takes place after the healing of the wound-at the which occured even when high doses of x rays were used, producing lethality in 75-80% of cases. The course of radiation sickness in the irradiated dogs also did not show a noticeable deterioration and unfavorable rted to radia tion sickness was of a somewhat longer duration, whereas the leukocyte count and the number of neutron animals only irradiated but not operated. The obtained experimental data give ground to assume that the typical abdominal operation (resection of a portation of the small intestine) in humans subjected to the action of ionizing radiation can be performed in the next few hours after irradiation without apprehension that the radiation affection will aggravate the postoperative course and results of the operation or that the latter will aggravate the course of radiation sickness. (auth)

• Research Organization: N.N. Burdenko Chief Military Hospital
• NSA Number: NSA-13-015876
• OSTI ID: 4242244
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 4; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANESTHESIA
BIOLOGY AND MEDICINE
DOGS
ETHERS
INTESTINE
LETHAL DOSE
LEUCOCYTES
MAN
MEDICINE
QUANTITY RATIO
RADIATION DOSES
RADIATION SICKNESS
REGENERATION
SURGERY
SURVIVAL TIME
USES
VARIATIONS
X RADIATION