THE EFFECT OF NARCOSIS AND NATURAL HIBERNATION ON THE RADIOSENSITIVITY OF ANIMALS
Journal Article
·
· Zhur. Obshchei Biol.
OSTI ID:4309630
The radiosensitivity of animals under deep narcosis and in a state of hibernation was investigated. Several hundred mice were exposed to doses of x radiation of by the administration of sodium Nembutal, Barbamil, Hedonal, Urethane, and ether both before and after irradiation was investigated. The effect of hibernation on the radiosensitivity of animals was investigated in the rodent, Citeilus major, following exposure to 600 r x radiation, and hedgehogs exposed to doses of 700 to 850 r. Data are tabulated and presented graphically. The use of narcosis after irradiation of the mice proved ineffective in reducing radiation damage. The use of Nembutal, Barbamil, and ether to produce narcosis during irradiation incrensed the resistance of mice to the action of 500 r x radiation as demonstrated by an increase in survival rate, delay in time of death, and faster restoration of body weight. The use of Hedonal and Urethane for narcosis was practically ineffective. The use of oxygen decreased in mice under narcosis induced by Nembutal and Barbamil. Deep Nembutal narcosis was found to delay, until the subject awakens, the early reactions against irradiation with massive doses of x radiation. The natural hibernation of animals did not increase their radioresistance to lethal doses of x radiation but delayed, until awakening, the onset of acute symptoms of radiation sickness. (C.H.)
- Research Organization:
- Inst. of Genetics, Academy of Sciences, USSR
- NSA Number:
- NSA-12-009646
- OSTI ID:
- 4309630
- Journal Information:
- Zhur. Obshchei Biol., Journal Name: Zhur. Obshchei Biol. Vol. Vol: No. 3
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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