THE BIOLOGICAL ACTION OF RADIOBARIUM

Journal Article · Wed Apr 01 04:00:00 EST 1959 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4237276

Moskalev, Yu I; Streltsova, V N

The specificity of radiation sickness in parenteral administration of various doses of radiobarium (Ba/sup 140/) was studied in experiments on rats. Values of acute (LD and chronic (LD 50/360 = 0.91 mu c/gm) doses were established. Acute radiation affection provoked by Baito is characterized by the development of a comparatively brief agranulocytic syndrome and hypochromic anemia, hemorrhagic diathesis, degenerative changes of parenchymatous organs, and early suppression of spermatogenesis. The subacute stage is characterized by the prevalence of restorative processes in the hematopoietic organs, effecting the normalization of peripheral blood picture (4Oth-5Oth day), atrophic changes of parenchymatous and generative organs, and the appearance of nonspecific inflammatory processes of bacterial nature. In the chrotic form of affection benign and malignant tumors (chondrosarcoma of the femur, papilloma of the urinary bladder and leukemia) develop in a number of animals. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-13-015874
• OSTI ID: 4237276
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 4, No. 4; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANEMIA
ANIMAL CELLS
BACTERIA
BARIUM 140
BIOLOGY AND MEDICINE
BLADDER
BLOOD FORMATION
BONES
CANCER
CARCINOGENESIS
CHONDROSARCOMAS
CYTOLOGY
ERYTHROCYTES
GONADS
HEMORRHAGE
INFECTIONS
LETHAL DOSE
LEUCOCYTES
LEUKEMIA
MITOSIS
PAPILLOMAS
QUANTITY RATIO
RADIATION DOSES
RADIATION INJURIES
RADIATION SICKNESS
RATS
REGENERATION
SPERMATOGENESIS
TESTES
TISSUES
TUMORS
VARIATIONS