LATE EFFECTS OF TOTAL-BODY ROENTGEN IRRADIATION. LONGEVITY AND INCIDENCE OF NEPHROSCLEROSIS AS INFLUENCED BY PARTIAL-BODY SHIELDING

Technical Report · Mon Sep 29 04:00:00 EDT 1958

OSTI ID:4236176

Lawson, B G; Billings, M S; Bennett, L R

Two hundred forty-two female Wistar rats were observed throughout their life span following 1,000 r hypoxic total-body or partial-body irradiation. Hypoxic radiation with superimposed anesthesia resulted in 67 percent 30 day mortality, compared to 9 percent mortality without anesthesia. Selection of the colony by acute postirradiation deaths did not influence the magnitude of late radiation sequelae as measured by lifeshortening. Growth retardation during the second postirradiation year was well correlated with lifeshortening. Life- shortening was observed after partialbody irradiation to and extent approximately proportional to the weight of radiated tissue. Nephrosclerosis was not observed unless the upper abdomen was included within the radiation field. Other than nephrosclerosis, a similar incidence of disease was observed at death in control and irradiated rats whether partial-body or total-body irradiated. (auth)

• Research Organization: California. Univ., Los Angeles. Atomic Energy Project
• NSA Number: NSA-13-018799
• OSTI ID: 4236176
• Report Number(s): AF-SAM-59-33
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
ANESTHESIA
BIOLOGY AND MEDICINE
BODY
CONTROL
DISEASES
INTESTINE
KIDNEYS
NEPHROSCLEROSIS
RADIATION DOSES
RADIATION INJURIES
RATS
SEX
SHIELDING
SURVIVAL TIME
TISSUES
WEIGHT
X RADIATION