EFFECT OF POST-IRRADIATION BONE MARROW TREATMENT ON RAT SPLEEN NUCLEIC ACIDS

Journal Article · Tue Dec 01 04:00:00 EST 1959 · Radiation Research

DOI:https://doi.org/10.2307/3570721· OSTI ID:4229005

Iammarino, R M; Berenbom, M

A study has been made of the ability of rat bone marrow, given to rats 1 to 2 hours after 400 r of whole-body x irradiation, to prevent or correct previously observed changes in the weight, RNA content, DNA content, and DNA purinepyrimidine composition of spleen. There was no evidence of prevention of these changes as determined 2 days after irradiation, but there was a slight beneficial effect on recovery as determined at 7 days by the significantly larger values for spleen weight, RNA content, and DNA content in irradiated rats which received bone marrow than in those which did not receive this treatment. Bone marrow given to irradiated rats did not prevent or correct the changes in the purine-pyrimidine composition of spleen DNA, which follow 400 r of whole-body x irradiation. (auth)

• Research Organization: Univ. of Kansas, Kansas City
• NSA Number: NSA-14-003466
• OSTI ID: 4229005
• Journal Information: Radiation Research, Journal Name: Radiation Research Journal Issue: 6 Vol. Vol: 11; ISSN 0033-7587
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOCHEMISTRY
BIOLOGY AND MEDICINE
BODY
BONE MARROW
DNA
EFFICIENCY
HETEROCYCLICS
IRRADIATION
NUCLEIC ACIDS
ORGANIC NITROGEN COMPOUNDS
PURINES
PYRIMIDINES
RADIATION EFFECTS
RADIATION INJURIES
RADIATION PROTECTION
RATS
RECOVERY
RIBONUCLEIC ACID
SPLEEN
STANDARDS
TRANSPLANTS
VARIATIONS
WEIGHT
X RADIATION