Developments in boron magnetic resonance imaging (MRI)

Technical Report · Wed Nov 01 04:00:00 EST 1995

DOI:https://doi.org/10.2172/421332· OSTI ID:421332

Schweizer, M.

This report summarizes progress during the past year on maturing Boron-11 magnetic resonance imaging (MRI) methodology for noninvasive determination of BNCT agents (BSH) spatially in time. Three major areas are excerpted: (1) Boron-11 MRI of BSH distributions in a canine intracranial tumor model and the first human glioblastoma patient, (2) whole body Boron-11 MRI of BSH pharmacokinetics in a rat flank tumor model, and (3) penetration of gadolinium salts through the BBB as a function of tumor growth in the canine brain.

• Research Organization: Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)
• OSTI ID: 421332
• Report Number(s): INEL--95/0561; ON: DE96003995
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BORON 11
BORON COMPOUNDS
BRAIN
DOGS
FRACTIONATED IRRADIATION
GADOLINIUM COMPOUNDS
GLIOMAS
IMAGES
LABELLED COMPOUNDS
MAGNETIC RESONANCE
NEOPLASMS
NEUTRON CAPTURE THERAPY
PATIENTS
PROGRESS REPORT
RADIOPHARMACEUTICALS
SALTS
SODIUM COMPOUNDS
TRACER TECHNIQUES
UPTAKE