Developments in boron magnetic resonance imaging (MRI)

Technical Report · Wed Nov 01 00:00:00 EST 1995

DOI:https://doi.org/10.2172/421332· OSTI ID:421332

Schweizer, M.

This report summarizes progress during the past year on maturing Boron-11 magnetic resonance imaging (MRI) methodology for noninvasive determination of BNCT agents (BSH) spatially in time. Three major areas are excerpted: (1) Boron-11 MRI of BSH distributions in a canine intracranial tumor model and the first human glioblastoma patient, (2) whole body Boron-11 MRI of BSH pharmacokinetics in a rat flank tumor model, and (3) penetration of gadolinium salts through the BBB as a function of tumor growth in the canine brain.

• Research Organization: Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)
• OSTI ID: 421332
• Report Number(s): INEL-95/0561; ON: DE96003995; TRN: 97:002186
• Resource Relation: Other Information: PBD: Nov 1995; Related Information: Is Part Of INEL BNCT Research Program annual report 1994; Venhuizen, J.R. [ed.]; PB: 83 p.
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BORON 11
UPTAKE
BRAIN
NEOPLASMS
GADOLINIUM COMPOUNDS
SODIUM COMPOUNDS
BORON COMPOUNDS
PROGRESS REPORT
SALTS
MAGNETIC RESONANCE
NEUTRON CAPTURE THERAPY
DOGS
PATIENTS
RADIOPHARMACEUTICALS
TRACER TECHNIQUES
LABELLED COMPOUNDS
GLIOMAS
FRACTIONATED IRRADIATION
IMAGES