Progress and Rate of Absorption of Radiostrontium Through Intestinal Tracts of Rats

Journal Article · Sun Nov 01 04:00:00 EST 1959 · Experimental Biology and Medicine

DOI:https://doi.org/10.3181/00379727-102-25301· OSTI ID:4212920

Cramer, C. F.; Copp, D. H.

Rate of absorption of Sr⁹⁸ from ligated loops of rat intestine, and rate of passage of Sr⁸⁹ through the intact intestinal tract were measured. Assuming only that absorption rate in ligated loops is reasonably the same as rate of absorption from that segment in the intact rat, the actual effective absorption was estimated. The highest initial rate of absorption occurred in the duodenum with jejunum, ileum, colon, and stomach following in decreasing order. Since the radiostrontium passed rapidly through the duodenum and jejunum, the largest actual effective absorption occurred in the ileum (65%), with smaller contributions by the jejunum (17%), colon (8%), duodenum (7%),and stomach (2%). Two factors were found to limit Sr/sup 89/ absorption. Movement of the isotope into gut segments caused slower absorption rate, and decreased absorption of Sr/sup 89/ was observed in each gut loop with time.

• Research Organization: Univ. of British Columbia, Vancouver
• Sponsoring Organization: USDOE
• NSA Number: NSA-14-003446
• OSTI ID: 4212920
• Journal Information: Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 2 Vol. 102; ISSN 1535-3702
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ABSORPTION
BIOLOGY AND MEDICINE
COLON
DIFFUSION
DISTRIBUTION
DUODENUM
INSTRUMENTS
INTESTINE
JEJUNUM
MEASURED VALUES
PERFORMANCE
RADIATION DOSES
RADIOACTIVITY
RATS
STOMACH
STRONTIUM 89
STRONTIUM ISOTOPES
VARIATIONS