PROGRESS AND RATE OF ABSORPTION OF RADIOPHOSPHORUS THROUGH THE INTESTINAL TRACT OF RATS
Rates of absorption and the movement of P/sup 32/ through the intestine of adult rats were measured. These two measurements were combined mathematically to estimate the effective contribution of each segment of the intestinal tract toward normal absorption of phosphorus. All parts of the intestinal tract were able to absorb P/sup 32/. The rate of absorption was greatest at the duodenum, followed by the jejunum, ileum, colon, and stomach in decreasing order. However, since P/sup 32/ passed rapidly through the duodenum and jejunum, less material was available to be absorbed, with the result that absorption was less effective in these segments than it was in the ileum. When the progress and rate of absorption were combined quantitatively, the greatest effective absorption was found to occur in the ileum (which absorbed 38% of the total), followed by the duodenum (29%), jejunum (25%), and colon (8%). Two factors which were found to limit P/sup 32/ absorption were: movement of the isotope into gut segments having slower absorption rate, and decreased absorption of P/sup 32/ in each gut loop with time. Similar factors had been found previously to limit Sr/sup 89/ absorption. (auth)
- Research Organization:
- Univ. of British Columbia, Vancouver
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-015361
- OSTI ID:
- 4041150
- Journal Information:
- Can. J. Biochem. and Physiol., Journal Name: Can. J. Biochem. and Physiol. Vol. Vol: 39
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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