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THE EFFECT OF CERTAIN NUCLEOTIDES AND NUCLEOSIDES ON THE REGENERATION OF HAEMOPOIETIC TISSUE AFTER IRRADIATION

Journal Article · · Biophysics (USSR) (English Translation)
OSTI ID:4209091
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The effect of transplantation or injection of certain nucleotides and nucleosides on haemopoietic tissue after irradiation was investigated experimentally. Their in vitro action was estimated by their effect on DNA synthesis in a bone marrow tissue suspension. In in vivo experiments the survival of irradiated and control animals was compared and the blood picture was examined. In the conditions under which our experiments were carried out, certain desoxyribonucleotides had a positive effect. Ribonucleotides had no substantial effect, while desoxyribonucleosides had a detrimental effect. (auth)

Research Organization:
Inst. of Biophysics, Czechoslovakian Academy of Sciences
NSA Number:
NSA-14-002308
OSTI ID:
4209091
Journal Information:
Biophysics (USSR) (English Translation), Journal Name: Biophysics (USSR) (English Translation) Vol. Vol: 4
Country of Publication:
Country unknown/Code not available
Language:
English

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Related Subjects

BIOCHEMISTRY
BIOLOGY AND MEDICINE
BLOOD FORMATION
BONE MARROW
NUCLEIC ACIDS
RADIATION EFFECTS
REGENERATION
RIBONUCLEIC ACID
SURVIVAL TIME
TISSUES
TRANSPLANTS