EARLY CHANGES IN THE LENS EPITHELIUM AFTER ROENTGEN IRRADIATION. A CORRELATED LIGHT AND ELECTRON MICROSCOPIC STUDY
The eyes of young albino rabbits were irradiated with 1,500 r x rays. The lens epithelium was examined 1, 4, 10, and 14 days after the treatment with the light microscope, in the form of Feulgen-stained flat mounts and with the electron microscope. Cells affected by ionizing radiation are randomly distributed throughout the epithelium but are more numerous in the equatorial zone. The changes occur in all cell constituents except the Golgi complex and range from slight alterations of the individual components to partial disintegration of the whole cell. The lesions gradually increase with time after irradiation in extent and in the number of structural elements involved. Changes in the organization of nuclei, nucleoli, mitochondria, endoplasmic reticulum, cell membranes, and the fine, low-density components are described in detail and correlated with the data resulting from the Feulgen reaction. (auth)
- Research Organization:
- National Institutes of Health, Bethesda, Md.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-004221
- OSTI ID:
- 4207383
- Journal Information:
- A.M.A. Arch. Ophthalmol., Journal Name: A.M.A. Arch. Ophthalmol. Vol. Vol: 62
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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