THE EFFECT OF X-RAY IRRADIATION ON THE COURSE OF VACCINAL PROCESS CAUSED BY THE ADMINISTRATION OF LIVING BRUCELLOSIS VACCINE TO ANIMALS (in Russian)
Investigations were conducted on white rats irradiated at doses of 300 to 600 r and guinea pigs irradiated at doses of 150 to 250 r. It appeared that immunizition with vaccinal brucella culture it the height of radiation sickness increases the death rate of the irradiated animals. As demonstrated by bacteriological examination, development of generalized vaccinal process in the irradiated and immunized animals pursued the same course as in the immunized non- irradiated animals. This procoss was manifested in the dissemination of brucella vaccinal strain in various organs. However the irradiated animals become cleared of the vaccinal culture at a somewhat slower rate than in the non-irradiated ones. in guinea pigs, irradiated privious to vaccination there was a slower formation of agglutinins with lower titre than in control non-irradiated animals. Opsonic phagocytic blood index was somewhat lower only in the animals irradiated 24 hours previous to the vaccination. When irradiating white rats 24 hours or 10 days in advance or 24 hours after the vaccination, a delay in the agglutinin production has been observed during the first days following the vaccination. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-14-004244
- OSTI ID:
- 4207119
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Vol. Vol: 4, No. 10; Other Information: Orig. Receipt Date: 31-DEC-60
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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