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Spleen-shielding in x-irradiation-accelerated experimental amyloidosis in mice

Journal Article · · Acta Pathologica et Microbiologica Scandinavica
An accelerating effect was previously found for x irradiation in total- body exposure to 400 r in mice made amyloidotic with caseinate injections. Results are presented from investigations with the use of lead-shielding of the surgically exteriorized spleen or of the body (only the spleen trradiated) under 400 r irradiation of mice with caseinate-induced amyloidosis. The conclusion is drawn that the accelerating effect of x rays in this kind of amyloidosis is not only part of a general stress reaction, but a direct one exercised on the cells of the reticular tissue, which are active in the production of amyloid.
Research Organization:
University Inst. of Pathological Anatomy, Copenhagen
Sponsoring Organization:
USDOE
NSA Number:
NSA-14-011443
OSTI ID:
4199203
Journal Information:
Acta Pathologica et Microbiologica Scandinavica, Journal Name: Acta Pathologica et Microbiologica Scandinavica Journal Issue: 1 Vol. 48; ISSN 0365-5555
Country of Publication:
Country unknown/Code not available
Language:
English

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