Advances in the robotic production of radiopharmaceuticals
- Washington Univ. School of Medicine, St. Louis, MO (United States)
A variety of robotic systems, including Zymark, Hudson Control Group, Anotech, and Questech formerly U.M.I, have been used as a reliable and safe way to produce radiopharmaceuticals. A robotic system`s ability allows it to produce a variety of radiopharmaceuticals on a routine basis including final preparation and quality control. With proper scheduling, a single robotic system can synthesize {sup 18}F-fluorodeoxyglucose, {sup 18}F-estradiol, {sup 11}C-acetate, {sup 68}Ga-citrate and at the same time control black box type syntheses such as {sup 15}O-butanol in a single day. A robotic system`s flexibility allows it to be used in designing and testing new syntheses, thus making the development of the new radiopharmaceuticals safer for the chemist. The development of Windows, a multi-tasking operating system for PC computers, allows a robot controlled by that computer to function simultaneously with a large variety of other systems. This increases the system`s ability to communicate with other systems and it allows for change without replacing the entire system. Improvements in robot technology has increased their reliability while making them competitive in price to other means of automation. Today a robotic system to produce {sup 18}F-fluorodeoxyglucose can cost as little as $55,000 U.S. depending on the cost of the hot cell.
- Research Organization:
- Brookhaven National Lab., Upton, NY (United States)
- OSTI ID:
- 41893
- Report Number(s):
- BNL--61149; CONF-9309170--; ON: DE95006634
- Country of Publication:
- United States
- Language:
- English
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