MAXIMUM PERMISSIBLE DOSE FROM THE VIEWPOINT OF RADIATION GENETICS

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Atompraxis (West Germany) Incorporated in Kerntechnik

OSTI ID:4181433

Marquardt, H

A brief survey is given of the problems of spontaneous and induced mutation in so far as they are important for an evaluation of maximum perraissible doses and concentrations. The maximum permissible concentration for radioactive isotopes, the relative genetic effectiveness of various types of radiation, and the effect of slight doses of radiation have not been sufficiently verified from the experimental genetic point of view. The induced total mutation stress in a population includes chemically induced and radiation-induced mutations: at present, the approximate extent of the chemically induced mutation rate cannot even be estimated. Owing to recent findings in mouse genetics, the concept of the doubling dose has become problematical. Thus the genetic data necessary for dealing with special questions of borderline-dose determination are not available in sufficient quantity; therefore the geneticist cannot recommend any dose exceeding basic radiation below which a genetic risk can be excluded with certainty. Rather, each single factor should be kept as low as possible. In regard to the fate of future generstions there is an urgent need of genetic research comparable with that in technology and atomic physics. (auth)

• Research Organization: Universitat, Freiburg i. B.
• NSA Number: NSA-14-008358
• OSTI ID: 4181433
• Journal Information: Atompraxis (West Germany) Incorporated in Kerntechnik, Journal Name: Atompraxis (West Germany) Incorporated in Kerntechnik Vol. Vol: 6; ISSN ATPXA
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

BIOLOGY AND MEDICINE
GENETICS
MICE
MUTATIONS
POPULATIONS
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
RADIOISOTOPES
STANDARDS