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U.S. Department of Energy
Office of Scientific and Technical Information

EFFECT OF X-IRRADIATION ON CELLULAR METABOLISM. Annual Report for Period August 1, 1958-July 31, 1959

Technical Report ·
OSTI ID:4177238
Further studies of the metabolism of human erythrocytes stored under standard blood bank conditions indicate that erythrocytes stored in blood packs have signtficantly lower levels of respiration than unstored cells Comparison of unirradiated and irradiated aliquots indicate that the increased respiration noted after 700 r or 1400 r was significant only at 0 (freshly drawn blood). 2 and 4 days Liver slices, used as an example of a radioresistant tissue, were subjected to 25, 100, or 200 x irradiation during respiratory measurements with no significant change in respiration. Spleen slices, a radiosensitive tissue, were exposed to 65, 250. or 500 r during respiratory measurements There was a significant depression in the respiration of spleen cells at all levels of radiation used in these in vitro tests. (auth)
Research Organization:
Ohio State Univ. Research Foundation, Columbus
NSA Number:
NSA-14-007215
OSTI ID:
4177238
Report Number(s):
AD-220750
Country of Publication:
United States
Language:
English