EFFECT OF METAL IONS ON THE RELATIVE UPTAKE OF Ca$sup 45$ AND Sr$sup 85$ BY BONE POWDER IN VITRO

Journal Article · Thu Nov 01 04:00:00 EST 1962 · J. Dental Res.

DOI:https://doi.org/10.1177/00220345620410061001· OSTI ID:4173208

Samachson, J; Lederer, H

ABS>The ratio of uptake of Ca/sup 45/ to that of Sr/sup 85/ by defatted bone powder in vitro was used as a parameter for the study of bone surfaces. To test the hypothesis that one difference between sites where ions exchange was the space available on the crystal surface, defatted bone powder was treated with metallic ions of different radii and then shaken with solutions containing Sr/sup 85/ and Ca/sup 45/. Alternatively, the metal ions were added to the same solution as the radioisotopes. Uptake was determined both with defatted bone powder and with anorganic bone. The ratio of Ca/sup 45/Sr/sup 85/ uptake was decreased by Be/sup 2+/, Cu/sup 2+/, Co/sup 2+/, Ni/sup 2+/, Mn/sup 2+/, Cd/sup 2+/, Zn/sup 2+/, and Pb/s up 2+/, unaffected by Mg2+, and increased by Ba/sup 2+/. Other factors also influenced the ratio, but, in general, the hypothesis suggested above appeared valid. Reproducibility of individual uptake values, but not of the ratio, was increased by more vigorous shaking. (auth)

• Research Organization: Veterans Administration Hospital, Hines, Ill. and Montefiore Hospital, New York
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-000028
• OSTI ID: 4173208
• Journal Information: J. Dental Res., Journal Name: J. Dental Res. Vol. Vol: 41
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BARIUM
BERYLLIUM
BIOLOGY AND MEDICINE
CADMIUM
CALCIUM 45
COBALT
COPPER
CRYSTALS
ION EXCHANGE
IONS
LEAD
MAGNESIUM
MANGANESE
METABOLISM
METALS
NICKEL
POWDERS
RADIOISOTOPES
SOLUTIONS
SURFACES
ZINC