CHANGES IN THE CEREBRAL CIRCULATION OF AN ANIMAL UNDER A WHOLE-BODY IONIZING IRRADIATION (in Russian)
Vascular disturbances in the animal brain were studied after a total single irradiation with a dose of 1000 r of x or gamma rays. Serial angiography and photography of pial vessels via a cranially implanted plexiglass port were used to evaluate the condition of cerebral vessels. The experiments were staged on rabbits and proved that, consequent upon a whole-body administration of 1000 r of ionizing radiation, clearly-pronounced circulatory disturbances occurred in the central nervous system. Each stage of the radiation sickness was characterized by definite hemodynamic disturbances. Immediately upon irradiation, while passing through the spasmodic stage occasioning a certain reduction in the blood flow, the cerebral vessels begin to dilate rather quickly. Twenty-four hours after irradiation the changes became stabilized and manifested themselves in an accentuated dilation of the venous portion of the vascular system. During the next stage, however, the circulation became normalized. At the height of the sickness the hemodynamic disturbances began to gather momentum, with the vessels tending to contract and to assume a beadlike shape. Further on, the vascular pattern acquired uniformity, the brain became anemic, and the blood flow diminished. The above disturbances were ordinarily observed 1 to 2 days prior to the death of the animal. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-14-015545
- OSTI ID:
- 4166753
- Journal Information:
- Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 5, No. 4; ISSN MERAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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