THE RELATIVE RADIOSENSITIVITY OF THE GENETIC STRUCTURE OF MAMMALIAN CELLS IN VITRO (in Russian)
The overall sensitivity of a mammal to radiation is expressed by a DL/ sub 50/30/ value, which is 300 to 400 r for the guinea pig (a little less than the LD/sub 50/30/ value for man), and is 550 r for the CC57 BR line of mice. Fresh cultures of fibroblasts of 1 to 1.5 month embryos of the guinea pig, and of 15 to 17 day embryos of the mice were fixed 38 hours after irradiation with a dose of 10 or 50 r, and the number of chromosomal rearrangements in anaphase and telophase was determined. Analysis of the data showed that the more radioresistant the animal, the smalier was the percent of chromosomal rearrangements per 1 g of tissue, which was 0.303 for the guinea pig at a 10 r dose, 0.157 for the guinea pig at a 50 r dose, and 0.072 for the mice at a 50 r dose. The corresponding figures are 0.158 for man, 0.053 for the rabbit, and 0.027 for the hamster. (TTT)
- Research Organization:
- Inst. of Cytology and Genetics, Academy of Sciences, Siberian SSR
- NSA Number:
- NSA-18-005041
- OSTI ID:
- 4162425
- Journal Information:
- Doklady Akademii Nauk SSSR (U.S.S.R.) English translation currently published in a number of subject-oriented journals, Journal Name: Doklady Akademii Nauk SSSR (U.S.S.R.) English translation currently published in a number of subject-oriented journals Vol. Vol: 152; ISSN DANKA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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