Glycopyrrolate in /sup 99m/Tc-pertechnetate brain imaging

Journal Article · Mon Sep 01 00:00:00 EDT 1975 · J. Nucl. Med., v. 16, no. 9, pp. 819-821

OSTI ID:4162145

Holmes, R A; Luth, C N

Glycopyrrolate, a synthetic anticholinergic agent, was administered parenterally to two groups of patients referred for /sup 99m/Tc-pertechnetate brain imaging to assess its ability to suppress pertechnetate uptake by the choroid plexus, oral mucosa, and salivary (parotid) glands. Pertechnetate activity was almost completely eliminated from the choroid plexus and mouth and appeared to be moderately reduced in the parotid gland. The drug can be given orally and may prove valuable in pertechnetate brain imaging. (auth)

• Research Organization: Medical College of Wisconsin, Milwaukee
• NSA Number: NSA-33-001057
• OSTI ID: 4162145
• Journal Information: J. Nucl. Med., v. 16, no. 9, pp. 819-821, Journal Name: J. Nucl. Med., v. 16, no. 9, pp. 819-821; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

*BRAIN-- SCINTISCANNING
*PERTECHNETATES- - TISSUE DISTRIBUTION
*RESPONSE MODIFYING FACTORS
*TECHNETIUM 99-- DIAGNOSTIC TECHNIQUES
550601* --Biomedical Sciences
Basic Studies--Medicine-- Unsealed Radionuclides in Diagnostics
BLOOD VESSELS
DRUGS
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ISOMERIC NUCLEI
N48830* --Life Sciences--New Tracer Techniques--Other
NUCLEAR MEDICINE
ORAL CAVITY
PATIENTS
RADIONUCLIDE ADMINISTRATION
SALIVARY GLANDS
TISSUES
UPTAKE